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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3558af399b499c208543e6f36b8c8b2e6a1365f7fa04f99914efd063d3e9e6ac' 
  AND token = 'S9Xa45DN//ULpzO8QXS3pTtf6/bEYu50fsWrRXutG20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}