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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e57c6191c2fdd5f8600de062e9dedb88b2c11bab7ff0b2cec5bb09f1611078f' 
  AND token = '5rQslE/ANElylciqrG91MhS2bOsjUqZj5l2HlT/0Ujk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}