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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5180a1b18d91829d941f34e360f3f4ac08b3a40911eec9ea0d266074ab21db74' 
  AND token = 'DjHPag26KleGTACAb0lz01BW1MHXBxmow2NwFQlcH+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}