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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41257ef0dabdb83059cc9a7a03f9221125a90346d5931ab53f462aba12ca6d20' 
  AND token = '8Kh7DPbDwsHM6dt31oJ9cpciXixuC6wzwfLFKbajyRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}