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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad06967a5148f5151a69e74286693ae0e66436743cd075a5792fee02b746717' 
  AND token = 'OzO8mK1U3ciM+EOIaA0L2jy3wvNsh8HVKIKhQF3XSuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}