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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5edac336a4681c2539fe6fe50619cb1135a47022b7d44dcd6c3b7cd082a37935' 
  AND token = 'wj+rFC5XSZ0r2NMZOczn1uMyGHR++qYeb7DuJKAzKkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}