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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7777dcbf3cd83551441b83c57f43b60e155b65d46f82c1ad26ca7aab47de7ad' 
  AND token = '4dPx9UT/DkWAYb2hmCNahMhWH7dLdZhR+3ifguHh2Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}