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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2609f1a6e8b1ceb3b49225b7f02993c66539d320f15ee869c13096bc13c8c18c' 
  AND token = 'H5Uv5swTAg6Yv8iLqdpRjWDqvdp5uPvS2pBIDTv9CWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}