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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5070f6a5e5c0a58d08c5dcedbab5e2478d997adce88307be464425403dc9009b' 
  AND token = '7b+oo6Q0smQnDJlZp3vLxS1v1t/3H38hq8YYsegyMrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}