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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fcefb134157a9c70f3bebd3e9d9bff7b0caaa740cd1c467b61bd3292d0c4614' 
  AND token = 'DTx+7tDeNDVfu+rYDBeYIpDd4rSW5jFmvivVU9LXb1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}