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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0fa3188f023553e4f23f82eeffe59f3cd33c03ae1ca54aea98e0afa4af445c' 
  AND token = 'MPMG0FvteeQlO6eqYCz/ajjCJ5XsuUZe3FMvTPyHwz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}