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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87c3b86bb6060a8f05341119d4a72b9f2a6a589affa05974e9d4efd0acbf96bd' 
  AND token = 'rtij6qoPqBHIx3MThg1/rlF408Ra7KFD0GhvuTnlM1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}