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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '720fa0c4e6ba2f266d638b498bcc42d01ba5c140be6eac061beacdba6dd9fcc1' 
  AND token = 'fhRvP2mY/YfBm6ST6/vienB12Vcn5Rm+25W7eF8LEZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}