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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fdfa74efebe3477b8e8f0cb6ee780ac7368fde8f7417ca6180c7f1f24ac7184' 
  AND token = 'UkUatfFeOqxifrmyBC8IQ5l2dxjvrdvGPhkE/CNJd7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}