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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66edd638e1dcf0b36dbd71d5f94e3781d93572e1474d66094febf20a9680ed19' 
  AND token = 'EaY4joup6OHUiV1IvGhXY9RfuC4ZYkTUb8wZkHFSIcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}