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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f296fdee36e3be2b0ed6b73b878099ce5b289bf4905c663ba1f67c97d4301788' 
  AND token = 'uMf7iAICSZ/S3o00c6ot+2m/GHjLgBbLycjC1ZPxhxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}