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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f44a67c9882ee1faa10fce66f3d9da98595765cd124456d2a349df64a3f140' 
  AND token = 'F9WTbBi6Aq4ES/FzRYaYLy9hkuWVh5upC26huePpXhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}