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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5382b9b0fcf14163333ef1f420fd8ce0b7cd8a5c9ff2ad75e0aa6c833545b016' 
  AND token = 'qZVYzxcFZHmPkBxytMdK0PS7/rQ9xkTrFZRbnbZEDjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}