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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604d7ce80b05401c7cfae8fdc9e9f58692f8e7b61aadb6bc8d39f7e6e49091f3' 
  AND token = 'ETkJRP6STOpt+WJ9dAiugpAny6pix6797AchJsQvCes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}