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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd143b8c22609d5da9b057d7ecaa11afa54ec1e0db9d64be5b1e2c681d3f635' 
  AND token = 'Hl0VO6+5iRX5szkGkMqHQ/pBt7q4JWHPWnvHALiXcEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}