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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab21bb628988350a3b5377e9841b016bf73d211bffc623066f3da9cd0dbedfcd' 
  AND token = 'q/AlmhtA4mo+KnMMpLouTnyhgOiY3Ui9hMa+kr7HqP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}