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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b48950d4f0408b30fa678972aea4d2d1d5337f422649f88286d701fe2360f81' 
  AND token = 'sWcXVnQlIqAa6Os/Her/VcxIeT7rdy8MO6m/hryikc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}