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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d48f8a6e8d3a9283d9449736d6bb01b3325974337d8c3d90f2e9f2c33e909a' 
  AND token = '4H0Q4RQVBj/S0Wgp4Ii1La1Y89bJ7Ri98Mq61TxKnXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}