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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65db86b1f9063fdc64b51a68a3a2f0b2b5942d3391a94bee249a238bd4623e1c' 
  AND token = 'T9mX0QobmXktZ3nayjVj2PAyDz4+ptdnEJ6vxqu3BBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}