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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46fe588e67abb20276376511705f72170e19e657af34e53200d3b4787cf3321' 
  AND token = 'pB1bBuxbDtgtPBK/4uZwUzNwC+HJCmEa7Uxf/FtryN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}