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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fe5dd9a66e105bd53c1aec53d9a3cb0159282462335c67a03eb68913bf9b921' 
  AND token = 'iapmUpcY8+KwH8L6p0bs1at71aB32kY0tZL+nIty80M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}