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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6e580650dc8812126cf75289ac0b2eef6eb8af2e2414056b0c6e4c6fbfb4266' 
  AND token = 'VznyfYxvP+1IKYa0T+9jj1D9T9cEL6nfP6SoiqOALWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}