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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd349b6738f00757c9c34a72dd7c683c25ef2179e66be1c3f925e2f58517f9be5' 
  AND token = '/b0crG+Es0Xe+FINePpbFsoAJh6TUusqiwcuhjnr/Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}