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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4202f3c222706e9710baa82eb7a754ad6145a0849500f767dbb5f7dfdf5d200' 
  AND token = '3qE4ED19JYbzVGOPo2+/8zzxmryapq+ZsIrTeiSWiZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}