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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f93e829b82397289cf3ceff2be24690cb1033a5669d4f6239175502c79f5b6' 
  AND token = 'udf3zlWeFNeV+BAARpiSOrPleNZv7uDhOj1YLiN53po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}