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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '271d77359842c5b9c54229ec3ea51c8cdda6d00b8cfb77296e977bae480aaa3d' 
  AND token = 'vcxVVkUEhW0YJKik9apBbS2YlrLj5T2OP6AaVGp/JNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}