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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd72573eab3b79b68a83bf71281958e96ad7cb0e58e83e2a87e3ccdd6c95697' 
  AND token = '+lfRBCn1RXimaeF4Ii9XESmQQEKvo/qU6yCGN2QCx40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}