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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d03add30521ac393588fbbdc82b19f05de2a5a02f0ada1491535da95c1d3b1' 
  AND token = 'gBY1pjFK4SGH/mFGEFMRZPnTxag/UUJSILtyXcqFq1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}