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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff8afec138e3ea0a71a955b855ff9f58fc81e80a5887e00f4904b77dd9ffe2a' 
  AND token = 'dr7v4VEpgQgHEtaI0EOaftjP/Py5rYa0RO/Cz7SqkqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}