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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a3d89e1f4127ab923c6d262c56355f8ce2f8a349753826155827ca9721499c6' 
  AND token = 'KDFZx5EeYUy8a43yzG6qLcxKFU8YNVGPKlGQhV8ypmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}