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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a39c5303304f47c1f8594e81e6e4010348ec3b0e19f81c51c25e86cab5377b0' 
  AND token = 's5p5/h9fgHH/oyoHE7trH413iatHTL2Z0CbdD8euCDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}