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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f6060b055582136d489a441474173eb3506d4a587a31391f6adf20a2b93cc20' 
  AND token = 'V2i2P055X4fWLNJ5H6fKGyjSPzRB7dfeV1LqUhTx7RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}