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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfb51353e7d0458aaa80aa9a2f44353550179cf5332fa0b915a5ebfb4afadf70' 
  AND token = 'CIdcUy6X2/wWNt6ML6yO8ShDz8cCHvhEaO+4pygSKhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}