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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd7ff8701d1618632d3777fab65dde304be6980d2024183ac1c56bf20d9a764' 
  AND token = 'v7YJzzjIvl7TmjfjxOWU8QM6Hx9pi542IVNo7Ngb8Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}