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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9fef869652d762a5272a254d89e21519b5a1e67fea521ba9f2b8554ba2cf55' 
  AND token = 'CwT31Eymip0M7npsU+uM528OKIckwFRG+16F7I1a8Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}