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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '196a9cb604d5de6cf1fa11e6c790d46d564f718f0fe64e209aa3ae763510bb54' 
  AND token = 'W5LM17M8hjr/F0fsYfDVmv0eOx6+7p/T6QpgMC1TFvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}