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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff074b90f08c38dc38df9138e48d8f1f21de5492b5405729b55fac7c53dd1a4' 
  AND token = 'B0B53V+u1F0j14dAm6OfijTu5ZmUKd+TBVNsK2aKmH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}