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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1a1793068ad5e375b2d4a05b18973f39bef1315e889b9fdbfad90a4627ec40d' 
  AND token = 'FNsZjR8D7O+y5ZC+VF9nrzdPqKlXZ78qZe8iSIpdJFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}