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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c068ab48684f4c9c41ecacbc3be7e21dcef84c1a265ca0c8748d6c98864fd785' 
  AND token = 'qvfdBsAizi3Xfe7e5Sd2cgtWPlXa3NywUmPSRphPMKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}