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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2cfa000d8cca0f94b6bc3b106aab62ed06e8bf0351ebcb7443d6fcc3b69d5f7' 
  AND token = '2sEn+lJfFOfqhRlyfHVBGgYEgjyG+3w0rdoewTk7d2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}