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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efed195747d654de2d4488cf860cc1f0b09cea609b1d6729dd0c8c4aa880dbae' 
  AND token = 'hEHT1LFfX6YoxU+5wFvI2eIPRmsM5iYVFUwIu7o/9x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}