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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '719c0162134d219610a7a78a01c70218ff0f4a949f53437f056be3f424a6eb77' 
  AND token = 'gtY7FY6TnnEmbTvbU576eSRJCZadl4EH+DtadAo4Iv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}