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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '710cd3241224dbb7744551d22c566c94e6ea7afb8245c25765cb3dd322279476' 
  AND token = 'TEd7zSVFHN55lH4b3SeiIKAimi7+xQ5YShvDOoWqRvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}