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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2ffb2ec3801da288017123a99aa00dc031a541f2e4887d5fe0d8ca0a6c4276b' 
  AND token = 'wu+CzOStFr/RUAvrowWgiANc1lP6soz76q1YsMOX6So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}