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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258e300435ec59878b645c870147e1b9c0e2e8ea1c938f8eab676774064556ca' 
  AND token = 'bDjHsxBjsMrV5kVvLn9u+jGfDDZ3GGcPvg6lyeFGOmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}